D-Ribose L-Cysteine Attenuates BPA-Induced Memory Deficit in Mice

1Delta State University, Abraka

Bisphenol A (BPA), a commonly used industrial chemical, has received widespread attention for its harmful effects on human health, specifically its role in neurotoxicity and cognitive deficits. BPA's negative effects include oxidative stress, endocrine disruption, and cholinergic dysregulation, all of which impair memory and learning skills. This study looks into the neuroprotective qualities of D-Ribose L-Cysteine (DRLC), a chemical renowned for its antioxidant activity and capacity to boost glutathione synthesis. Male mice exposed to BPA were treated with DRLC at varied doses, which resulted in significant increases in memory function, antioxidant defense restoration, and oxidative stress marker reduction. The study's findings indicate that DRLC could be a promising treatment drug for preventing BPA-induced cognitive impairment. Furthermore, this study emphasizes the necessity for additional investigation into the mechanisms of DRLC and its potential application in treating various neurotoxic diseases.